Lt. Darci Tierney said in a news release that officers were near the Lothrop Social Hall at 11:47 p.m. Friday when shots were fired in the area.
Officers found two people with gunshot wounds inside the building. Those two were taken to the Nebraska Medical Center, but 21-year-old Jacquez L. Lewis died of his injuries.
Two other victims went by private vehicle to Creighton University Medical Center. The news release said their injuries were not life-threatening.
Police said one of the victims is a 14-year-old girl. Tierney said in the release the investigation is ongoing.