The accident happened shortly after 11 p.m. Saturday in the intersection of O and Cotner streets in Lincoln.
Lincoln Police Capt. Michon Morrow says the driver of the motorcycle, 21-year-old Tyler Wilson, ran a red light before his motorcycle hit the Jeep Liberty as that vehicle turned left onto O Street.
Wilson was taken to a Lincoln hospital for treatment. His female passenger, Jessie McCain of Lincoln, died at the scene of the crash.